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Pharmaceutical API Lovastatin Antihypercholesterolemic CAS No. 75330-75-5

Pharmaceutical API Lovastatin Antihypercholesterolemic CAS No. 75330-75-5 CAS NO.75330-75-5

  • FOB Price: USD: 20.00-35.00 /Kilogram Get Latest Price
  • Min.Order: 25 Kilogram
  • Payment Terms: L/C,T/T,MoneyGram
  • Available Specifications:

    99(1-25)Kilogram99(26-100)Kilogram99(101-1000)Kilogram

  • Product Details

Keywords

  • 75330-75-5
  • Lovastatin Antihypercholesterolemic
  • Antifungal

Quick Details

  • ProName: Pharmaceutical API Lovastatin Antihype...
  • CasNo: 75330-75-5
  • Molecular Formula: C16H23FN2O2
  • Appearance: white powder
  • Application: Pharmaceutical Intermediates
  • DeliveryTime: WITHIN IN 3 DAYS
  • PackAge: AS YOUR REQUIREMENT
  • Port: TIANJIN
  • ProductionCapacity: 1000 Metric Ton/Month
  • Purity: 99.9
  • Storage: Seal and store away from light
  • Transportation: CIF,CFR, FOB
  • LimitNum: 25 Kilogram
  • Grade: Industrial Grade,Food Grade,Pharma Gra...

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Details

Product name: Lovastatin
CAS: 75330-75-5
Chemical Properties: White Solid
Molecular Formula: C24H36O5
Molecular Weight: 404.54
Uses: An antihypercholesterolemic agent. A fungal metabolite, which is a potent inhibitor of HMG-CoA reductase
antiarrhythmic
Lovastatin (mevinolin) is a metabolite first isolated from Monascus ruber and later found in several other fungal species. Lovastatin is a potent inhibitor of HMG-CoA. HMG-CoA reductase is the rate-controlling enzyme of the mevalonate pathway, responsible for the biosynthesis of cholesterol. Lovastatin was developed as a drug as a hypolipemic agent.
anti-hyperlipoproteinemic, 3-hydroxy-3-methylglutaryl coenzyme A (HMG-CoA) reductase inhibitor
 
Biological Activity Potent, competitive inhibitor of HMG-CoA reductase (K i = 0.6 nM) therefore decreases cholesterol biosynthesis, in vitro and in vivo . Decreases CDK2, 4, 6 and cyclin E levels and induces G1 arrest and apoptosis in tumor cell lines in vitro .

USAGE:

1-BOC-4-(4-FLUORO-PHENYLAMINO)-PIPERIDINE was used as a pharmaceutical intermediateitor 

Product Name Tert-Butyl 4- (4-fluoroanilino) 
CAS 288573-56-8
Molecular formula C16H23FN2O2
Molecular Weight 294.36400
Boiling point 92-96 oC (0.6 Torr)
Flash point 110.9±21.8 oC
Melting Point 58.5-59.0 oC
PSA 41.57000
LogP 3.64800
Appearance Light yellow crystalline powder
Accurate quality 294.17400
Packing Aluminum foil bag or as your requirement
Usage Mainly use in Pharmaceutical Intermediates/medical intermediate/ Research purpose
Type Pharmaceutical Intermediates
Storage The warehouse is ventilated, low temperature and dry, and stored separately from food materials

 

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