China (Mainland)
Humanin (human) 330936-69-1 CAS NO.330936-69-1
- FOB Price: USD: 10.00-15.00 /Kilogram Get Latest Price
- Min.Order: 25 Kilogram
- Payment Terms: L/C,D/A,D/P,T/T,MoneyGram
- Available Specifications:
99%(1-10)Kilogram99%(11-100)Metric Ton99.9%(1-10)Metric Ton
- Product Details
Keywords
- CAS NO.330936-69-1
- Humanin (human)
- C119H204N34O32S2
Quick Details
- ProName: Humanin (human) 330936-69-1
- CasNo: 330936-69-1
- Molecular Formula: C119H204N34O32S2
- Appearance: White Powder
- Application: API
- DeliveryTime: 3-10working days
- PackAge: 1kg/foil bag,25kg/drum(bag)
- Port: Tianjin
- ProductionCapacity: 50 Metric Ton/Day
- Purity: 99%
- Storage: Store in dry ,dark and ventilated plac...
- Transportation: by sea or air
- LimitNum: 25 Kilogram
- Moisture Content: 0.1%
- Impurity: 0.1%
- China Hebei: Shijiazhuang Wego
- Molecular Formnla: C119H204N34O32S2
- Product name: Humanin (human)
- CAS NO.: 330936-69-1
Superiority
About us:
Our company offers variety of products which can meet your multifarious demands. We adhere to the management principles of "quality first, customer first and credit-based" since the establishment of the company and always do our best to satisfy potential needs of our customers. Our company is sincerely willing to cooperate with enterprises from all over the world in order to realize a win-win situation since the trend of economic globalization has developed with anirresistible force.
Hebei Wego Import and Export Trade Co., Ltd. is one that production and sales as one of the large high-tech joint-stock enterprises chemical, it is located in the nine provinces of Wuhan, Hubei Province, Tongqu East Lake Technology Development Zone, the traffic is very convenient.
Hebei Wego Import and Export Trade Co., Ltd covers an area of 95 acres, the proposed construction of the plant will be GMP standards, the factory environment clean and tidy, rational layout, with large and medium-sized production workshop and repocessed shop. It is equipped with advanced equipment quality inspection and research center. Those products of both quality and technical content have reached the domestic advanced level. Products sell well all over the country and exported to Europe and the United States and Southeast Asia, and so on.
Our company invested heavily and manpower for research and development to meet the needs of the market fine chemicals, bio-chemical, pharmaceutical intermediates also other new products, new technology. High-level research and development team, first-class laboratory equipment, a good atmosphere to ensure research and development R & D strength, the current production of products. Our company′s research and development have reached the domestic advanced level. Even some products reached the international advanced level.
Our Advantages:
We have clients throughout the world.
1. Professional service and rich experience make customers feel at ease, adequate stock and fast delivery meet their desire.
2. Market feedback and goods feedback will be appreciated , meeting customers' requirement is our responsibility.
3. High quality, competitive price, fast delivery, first-class service gain the trust and praise from the customers.
5.Sample order are welcome.
6.NMR,HPLC and COA can be supplied
7.We can supply sample for testing
8.We promise 100% received,and 100% resend or refunds if parcel is not received.
Our Services:
Quality
The company is based on honest service, product quality is the highest requirement,and product variety is rich.
Price
We have the best price, if you need more quantity then we can also provide you with a more favorable price.
Service
Lower MOQ.
Door to Door service.
Details
Product details:
| cas | 330936-69-1 |
| Name | Humanin |
| Synonyms | 1-24-Protein humanin (human) |
| MF | C119H204N34O32S2 |
| Purity | 99% |
| Application | Humanin (HN) is a cytoprotective 24 amino acid peptide which was originally isolated from a cDNA library constructed from nervous tissue of a patient with familial Alzheimer's disease (AD). Since then, it has been identified in different species such as mice, nematodes and rats (Niikura et al., 2004). The rat humanin homolog rattin (HNr) is a 38 amino acid peptide encoded and translated from an open reading frame (ORF) within the mitochondrial 16S ribosomal RNA (rRNA) gene (Caricasole et al., 2002; Paharkova et al., 2015). Several studies have demonstrated that HN is a potent pro-survival factor for neurons exposed to multiple cell stressors, such as Aβ oligomers and over-expression of familial AD-related genes serum deprivation , stroke and N-methyl-D-aspartate (NMDA)-induced excitotoxicity. HN and its derivatives have also proven to be beneficial in ameliorating cognitive impairment induced by Aβ, muscarinic receptor antagonists and aging in rodents. Moreover, HN and HNr were reported to prevent Aβ-induced spatial learning and memory impairments in rats by a mechanism involving changes in long-term potentiation , synaptic protein expression, dendritic branch number and spine density in the hippocampus . It has been reported that HN exerts its neuroprotective action from the extracellular space through binding to a trimeric IL-6-receptor-related receptor(s) on the cell surface involving the receptor for ciliary neurotrophic factor α (CNTFR-α), WSX-1 and glycoprotein 130 kDa (gp130) subunits and further modulation of tyrosin kinase, ERK1/2, AkT, STAT3 and JNK signaling cascades. HN has been ubiquitously detected in different adult tissues with high metabolic rate, including skeletal and cardiac muscle, cerebral cortex, hippocampus and liver both in humans and in rodents. The mechanisms regulating HN expression are not fully elucidated. It has been shown that HN levels decrease with age in human and mice plasma as well as in the rat hypothalamus Also, there is a sexual dimorphism in the expression of HN in rat anterior pituitary cells, suggesting that sex hormones are involved in the regulation of HN biosynthesis in this gland In the brain, HN has been widely localized both in neurons and glial cells, albeit the former only in pathological conditions Thus, glial cells have been suggested to be the main production sites of this peptide in the brain in physiological conditions However, astroglial HN expression and release and the regulation of such processes by ovarian hormones have not been studied so far. |
Package:
Liquid:
25kg per unit
170kg per unit
1 ton per unit
Iron drum & plastic drum packaging
Packing:
1. Inner double plastic bags----25kg/Fiber drum (35*35*45cm, GW: 28kg, NW: 25kg);
2. Inner double plastic bags----5kg/Aluminum foil bag (GW: 6.5kg, NW: 5kg).
3. Inner double plastic bags----1kg/Aluminum foil bag (GW: 1.5kg, NW: 1kg).
Delivery:
1. Stock products are normally shipping within 3 working days.
2. For rush delivery, please contact our sales team for particular arrangement.
Shipping Details:
1. We ship goods via DHL, Fedex , UPS, TNT, China post, NL Post and other couriers, weight from 10g to 1000kg or even bulked.
2. Shipping details & shipping documents will be provided and sent by email.
3. We keep tracking the shipment until clients well received.
4. After years export shipping experience, with professional and experienced cooperated forwarders, we ensure that goods can be delivered in multiple ways safely and efficiently.
FAQ
Q1 Can i get some samples
A1 Yes, we can supply the free sample, but the shipping cost be paid by our customers.
Q2 How to start orders or make payments
A2 Proforma invoice will be sent first after confirmation of order, enclosed our bank information.Payment by T/T, or Paypal.
Q3 How to confirm the Product Quality before placing orders
A3 You can get free samples for some products,you only need to pay the shipping cost or arrange a courier to us and take the samples. You can send us your product specifications and requests,we will manufacture the products according to your requests.
Q4 What's your MOQ
A4 Our MOQ is 1kg. But usually we accept less quantity such as 100g on the condition that sample charge is 100% paid.
Q5 How about delivery lead time
A5 Delivery lead time: About 3-5 days after payment confirmed. (Chinese holiday not included).
Q6 Is there a discount
A6 Different quantity has different discount.
Q7 How do you treat quality complaint
A7 First of all, our quality control will reduce the quality problem to near zero. If there is a real quality problem caused by us, we will send you free goods for replacement or refund your loss.
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